Preparation and <i>In vitro</i> Evaluation of Theophylline Loaded Gastroretentive Floating Tablets of METHOCEL K4M
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چکیده
منابع مشابه
Preparation and evaluation of gastroretentive floating tablets of Silymarin.
The present study performed by preparation and evaluation of floating tablets of Silymarin as model drug for prolongation of gastric residence time. Floating effervescent tablets were formulated by various materials like hydroxypropyl methylcellulose (HPMC) K 4M, K 15M, psyllium husk, swelling agent as crospovidone and microcrystalline cellulose and gas generating agent like sodium bicarbonate ...
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The low bioavailability (15%) and good solubility of Domperidone Maleate in acidic pH following oral administration favours development of a gastro retentive formulation. Gastroretentive floating matrix tablets of Domperidone Maleate were successfully prepared with hydrophilic polymers like HPMC K4M, HPMC K15M and HPMC K100M. From the Preformulation studies for drug excipients compatibility it ...
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Floating matrix tablets of norfloxacin were developed to prolong gastric residence time, leading to an increase in drug bioavailability. Tablets were prepared by the wet granulation technique, using polymers such as hydroxypropyl methylcellulose (HPMC K4M, HPMC K100M) and xanthan gum. Tablets were evaluated for their physical characteristics, viz., hardness, thickness, friability, and mass vari...
متن کاملFormulation and Evaluation of Controlled Release Floating Tablets of Lamivudine Employing Hpmc K4m and Sodium Alginate
Lamivudine, a BCS Class I synthetic nucleoside analogue, has a a short biological half-life of 5–7 and is mainly absorbed in the upper gastrointestinal tract. The purpose of the study is to develop a controlled release floating tablets of lamivudine employing HPMC K4M and sodium alginate. The floating tablets of lamivudine were prepared employing HPMC K4M and sodium alginate as matrix formers a...
متن کاملFormulation Development and In-Vitro Evaluation of Gastroretentive Floating tablets of Atenolol
The purpose of the study was to prolong the gastric residence time and increase the bioavailability of atenolol by designing its floating tablets and to study the influence of different polymers on its release rate. It was selected as a model drug, because it is poorly absorbed from the lower GIT. The tablets were prepared by direct compression technique, using different polymers such as hydrox...
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ژورنال
عنوان ژورنال: Dhaka University Journal of Pharmaceutical Sciences
سال: 1970
ISSN: 1816-1839,1816-1820
DOI: 10.3329/dujps.v7i1.1220